甲妳攬牢牢！胚胎強力膠EmbryoGlue®
小兵立大功
作者華人健康網記者黃曼瑩／台北報導 |
華人健康網 – 2015年1月20日
【華人健康網記者黃曼瑩／台北報導】
甲妳攬牢牢！不孕婦女想求子，接受試管嬰兒技術，卻擔心胚胎不健康，恐影響著床，現在已經可以透過「胚胎強力膠EmbryoGlue®」幫忙，將胚胎固定在子宮壁上，並能降低胚胎因為子宮收縮被排出的可能，臨床統計，可提高約50%懷孕率。
1名40歲的張小姐，因為輸卵管因素曾經做過兩次試管嬰兒，都沒有成功，醫師告訴她胚胎非常好，但是，她卻非常納悶的說：「為什麼胚胎品質很好，都沒有辦法成功！」而且已經放進4個胚胎，經過婦產科醫師幫她做取卵、胚胎培養，也發現胚胎品質很好，基於前兩次沒有成功，這一次在植入胚胎的時候，使用由北歐VitroLife生產的「胚胎強力膠EmbryoGlue®」，把胚胎固定在子宮壁上，這一次成功懷孕了。
胚胎強力膠EmbryoGlue®主要成份為玻尿酸，輔助胚胎穩固著床
婦產科醫師蔡鋒博表示，胚胎強力膠的原理在於使胚胎培養液裡面提升玻尿酸的濃度，使胚胎跟子宮壁的粘著性增加。胚胎強力膠的主要成份為玻尿酸，只要在植入胚胎植時，同時混合、裹上一層胚胎強力膠，就可以輔助胚胎穩固著床。
玻尿酸屬於非蛋白質的黏多糖類，真皮層的基質，是絕佳保濕劑，能吸取本身重量400~1000倍之水分，屬水溶性大分子保溼成分（動物提取者分子量可能百萬以上，微生物發酵者則約10萬左右），無法滲入肌膚，其保溼能力較多元醇類來的佳。
附註
EMBRYOGLUE®
（http://www.vitrolife.com/en/Fertility/Products/G-SeriesTM-media/EmbryoGlue/）
EmbryoGlue® increases take-home baby rate
EmbryoGlue is an implantation promoting transfer medium with a unique combination of hyaluronic acid and recombinant albumin.
The addition of a high concentration of hyaluronic acid (HA) in a transfer medium, such as EmbryoGlue, increases live births after IVF according to a newly published meta-analysis from the independent research network Cochrane Collaboration. When using EmbryoGlue for transfer, there was an overall increase of 8% in the live birth rate, compared to a medium with low or no HA. The positive effect was seen regardless of embryo transfer day.
Learn how to use EmbryoGlue
EmbryoGlue is used at Cambridge IVF
How does is work？
EmbryoGlue® contains all nutrients and energy sources needed for an optimal embryo development. It contains a high concentration of implantation promoting hyaluronan, which is the major glycosaminoglycan present in the follicular, oviductal and uterine fluids. The physiological concentrations in these fluids provide high viscosity environments in the oviduct and uterus.
The synthesis of hyaluronan increases dramatically on the day of implantation and decreases to near basal levels by the next day, indicating that it is important for implantation.
Hyaluronan makes the difference
EmbryoGlue® has the basic composition of a rich blastocyst culture medium and contains a high concentration of hyaluronan and recombinant human albumin. It can be used for transfer of all embryo developmental stages, including embryos after assisted hatching, biopsy and cryopreservation. The use of EmbryoGlue® for embryo transfer will increase the clinical pregnancy rate and live birth rate.
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