Use of platelet-rich fibrin over skin wounds：Modified secondary intention healing（1）
Chirag B Desai1, Uma R Mahindra1, Yogesh K Kini2, Makarand K Bakshi1
1 Department of Oral and Maxillofacial Surgery, Rural Dental College, Pravara Institute of Medical Sciences, Loni, Ahmednagar, India
2 Department of Oral and Maxillofacial Surgery, Dr. D.Y. Patil Dental College, Mumbai, Maharashtra, India
Date of Web Publication 4-Apr-2013
CASE REPORT
Year : 2013 | Volume : 6 | Issue : 1 | Page : 35-37
Abstract
The healing process after any surgical intervention has always posed a challenge for the surgeons. In spite of the advances in wound closure techniques and devices, there is a crucial need for newer methods of enhancing the healing process to achieve optimal outcomes. Fibrin adhesives and Platelet concentrates have proven useful in various treatment modalities in the fields of microvascular and plastic surgery. This case report shows its unique use in the field of maxillofacial and cutaneous surgery. It shows an innovative technique of enhancement of skin wound healing by local application of Platelet-rich fibrin.
Keywords : Biologic dressing, modified secondary intention healing, platelet-rich fibrin
（http://www.jcasonline.com/article.asp?issn=0974-2077;year=2013;volume=6;issue=1;spage=35;epage=37;aulast=Desai）
How to cite this article:
Desai CB, Mahindra UR, Kini YK, Bakshi MK. Use of platelet-rich fibrin over skin wounds: Modified secondary intention healing. J Cutan Aesthet Surg 2013;6:35-7
How to cite this URL:
Desai CB, Mahindra UR, Kini YK, Bakshi MK. Use of platelet-rich fibrin over skin wounds: Modified secondary intention healing. J Cutan Aesthet Surg [serial online] 2013 [cited 2013 Sep 28];6:35-7.
Available from: http://www.jcasonline.com/text.asp?2013/6/1/35/110096.
Introduction
Despite the modern advances in wound closure techniques and devices, there is a vital need for newer methods of enhancing the healing process to achieve optimal outcomes. Wound healing is a complex sequence of intracellular and extracellular events regulated by signaling proteins. This process is, at present, not completely understood. One of the promising, but complicated areas of recent therapeutic development involves topical application of growth factors to enhance the normal healing process. This case report shows an innovative technique of enhancement of healing of skin wounds by local application of Platelet-rich fibrin（PRF）as a Biological dressing.
Case Report
A 30-year-old man who suffered a motorcycle accident, reported to the Department of Oral and Maxillofacial Surgery, presenting with an avulsive wound, approximately 0.5 × 1 cm in size, on the lower lip in the midline region with a disruption of the vermilion border and a white roll [Figure 1]. The depth of the wound was uneven with muscle tissue loss in some regions. The patient had no medical history. Primary closure could have caused pouting of the lip. Healing by secondary intention could have resulted in fibrosis and development of a hideous scar. Therefore, it was decided to treat the defect by local application of a PRF membrane.
Figure 1：Avulsive wound over the lower lip
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